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AICAR 50mg
₡ 43,169
AICAR 50mg is a research-grade peptide compound commonly studied in relation to AMPK pathway activity, cellular energy research, metabolic signaling, endurance-related research models, and mitochondrial function studies.This 50mg vial provides a larger research quantity for laboratory studies involving AICAR and its role in energy metabolism and cellular performance research.Verified COA AvailableFor laboratory research use only. Not for human or veterinary use.
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Product Information
AICAR is a research compound commonly studied for its relationship with cellular energy regulation and AMPK pathway activity. It is frequently included in laboratory studies focused on metabolic signaling, mitochondrial function, glucose metabolism research, lipid pathway studies, and cellular performance models.
In research environments, AICAR is often explored for its connection to AMP-activated protein kinase activity and how this pathway may influence cellular energy balance. These studies may involve areas such as mitochondrial response, metabolic adaptation, oxidative stress research, and endurance-related biological models.
AICAR 50mg offers a larger vial size for controlled research applications where a higher quantity is required. This strength may be suitable for extended protocols, repeated testing, or laboratory studies requiring more material than smaller vial formats.
The product is prepared for laboratory research use and packaged to support quality, stability, and product integrity.
This product is intended strictly for laboratory research purposes only and is not for human or veterinary use.
| Specification | Value |
| Product Name: | AICAR 50mg |
| Compound Type: | Small molecule / AMPK activator (nucleoside analogue) |
| CAS Number: | 2627-69-2 |
| PubChem CID: | 17513 |
| Molecular Formula: | C9H14N4O5 |
| Molecular Weight (g/mol): | 258.23 |
| Amino Acid Count: | N/A (small molecule — nucleoside analogue) |
| Amino Acid Sequence / IUPAC: | 5-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4-carboxamide |
| Synonyms / Other Names: | Acadesine, AICA-riboside, 5-Aminoimidazole-4-carboxamide ribonucleoside, ZMP precursor |
| Appearance: | White to off-white powder |
| Purity: | >=99% (HPLC) |
| Solubility: | Soluble in water (>7 mg/mL); slightly soluble in DMSO |
| Storage — Sealed: | Store at <= -20 C, sealed, away from light & moisture; stable ~24 months |
| Storage — After Reconstitution: | Refrigerate 2-8 C; use within 28-30 days; protect from light |
Specification
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Key Benefits
What You Get
1 vial containing 50mg of AICAR
Research-grade compound formulation
Larger 50mg vial option for controlled laboratory research
Suitable for AMPK, metabolic, and cellular energy research applications
Carefully packaged to help preserve product integrity
Verified Certificate of Analysis available when provided

AMPK Pathway Research
AICAR is commonly studied for its relationship with AMPK pathway activity. This makes it relevant for research focused on cellular energy signaling, metabolic response, and energy balance mechanisms.
Cellular Energy Studies
This compound is frequently researched in relation to cellular energy regulation, mitochondrial function, and metabolic adaptation. It is often selected for studies involving cellular performance and energy pathway response.
Metabolic & Endurance Research
AICAR is commonly explored in research related to glucose metabolism, lipid metabolism, endurance models, and cellular performance pathways. It is frequently used in laboratory studies focused on metabolic and energy-related research.
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Common Questions
Frequently Asked Questions
What is AICAR and what metabolic pathway does it target? +
AICAR (Acadesine) is a cell-permeable nucleoside analogue that is phosphorylated inside cells to form ZMP, which mimics AMP and activates AMPK (AMP-activated protein kinase) — the master regulator of cellular energy homeostasis. It is studied for its role in glucose and lipid metabolism, mitochondrial biogenesis, and exercise mimicry.
Does AICAR need to be reconstituted before use, and how? +
Yes. The 50mg lyophilized powder requires reconstitution. AICAR is freely soluble in water (>7 mg/mL). Add bacteriostatic water to your target concentration — for example, adding 5 mL gives 10 mg/mL. It can also be dissolved in DMSO for specific protocols. Use the reconstitution calculator on this page.
How many doses does a 50mg AICAR vial provide? +
With 5 mL water (10 mg/mL), the 50mg vial provides approximately 50 doses at 1 mg each, or 25 doses at 2 mg each. Research protocols vary widely — AICAR is sometimes used at higher doses in metabolic studies..
Is AICAR the same compound as is found naturally in cells? +
Yes and no. AICAR (the nucleoside, CAS 2627-69-2) is exogenously supplied. Its phosphorylated intracellular form ZMP (AICA ribonucleotide, CAS 3031-94-5) is a naturally occurring intermediate in purine biosynthesis. The supplied AICAR is converted to ZMP by adenosine kinase once inside cells.
How should the reconstituted AICAR solution be stored? +
Refrigerate at 2-8 C after reconstitution and use within 28-30 days. Protect from light. Store the sealed lyophilized vial at <= -20 C before use. AICAR is more stable than most peptides in aqueous solution but should still be kept cold and protected from repeated freeze-thaw.







