5-Amino-1MQ Technical Specification Sheet
Complete chemical, physical and handling data for 5-Amino-1MQ as supplied including, CAS number, molecular formulas, salt form, purity, solubility and storage, covering both vial sizes.
This sheet describes 5-Amino-1MQ as manufactured and supplied. Batch-specific analytical results are reported separately on the Certificate of Analysis issued with each lot. Supplied for laboratory and research use only.
The evidence base here is preclinical only
Everything published on 5-Amino-1MQ comes from cell culture and rodent models. There are no controlled human trials of this compound, and its safety profile in people is not established. That is a materially different position from the GLP-1 compounds elsewhere in this catalogue, several of which have large clinical datasets behind them. Anyone evaluating this compound in a context involving human health should discuss it with a qualified healthcare professional first.
5-Amino-1MQ is the odd one out in this catalogue. Almost everything else here is a peptide — a chain of amino acids. This is a small molecule: a single quinoline ring system with a methyl group on the nitrogen and an amino group at position 5. It works by inhibiting an enzyme rather than by binding a receptor.
That enzyme is nicotinamide N-methyltransferase, or NNMT, which consumes nicotinamide that would otherwise feed NAD⁺ production. Blocking it is the reason the compound appears in metabolic research.
This page is the technical reference — identity, purity, handling and storage. Both vial sizes contain identical material at the same purity specification. Only the quantity differs.
Product Identification
| Specification | Value |
|---|---|
| Product Name | 5-Amino-1MQ |
| Product Code | PCR-A1MQ-5 · PCR-A1MQ-50 |
| Compound Type | Small molecule — quaternary quinolinium; not a peptide |
| IUPAC Name | 1-Methylquinolin-1-ium-5-amine iodide |
| Synonyms / Other Names | 5-Amino-1MQ; 5-Amino-1-methylquinolinium iodide; NNMTi |
| Molecular Target | Nicotinamide N-methyltransferase (NNMT) |
| Physical Form | Lyophilized powder, single vial |
| Research Category | Metabolic research compound |
Chemical & Physical Properties
| Specification | Value |
|---|---|
| CAS Number | 42464-96-0 (iodide salt) |
| PubChem CID | 950107 (cation) |
| Molecular Formula | C10H11N2+ (cation) · C10H11IN2 (iodide salt) |
| Molecular Weight | 159.21 g/mol (cation) · 286.11 g/mol (iodide salt) |
| Salt Form | Supplied as the iodide salt; the quinolinium nitrogen is permanently quaternised and therefore always carries a counter-ion |
| InChIKey | JPEZFBFIRRAFNR-UHFFFAOYSA-N |
| Physical State | Lyophilized solid |
| Purity | ≥ 98% by HPLC |
Two Molecular Weights, One Compound
5-Amino-1MQ is quoted at two different molecular weights across the supplier market, and picking the wrong one is a large error rather than a rounding difference.
The active species is the cation, C10H11N2+, at 159.21 g/mol. But a quaternary quinolinium nitrogen carries a permanent positive charge, so the cation cannot exist on its own — it is always paired with a counter-ion. What ships is the iodide salt, C10H11IN2, at 286.11 g/mol.
Weigh out material using the cation weight and you will under-deliver by about 44%, because iodide accounts for that much of the mass in the vial. For anything gravimetric, use 286.11.
A note on "free base"
Some listings describe the 159.21 figure as the "free base". That is not chemically accurate here — a permanently quaternised nitrogen has no neutral free-base form. The correct term is the cation, and the distinction matters when you are reconciling one supplier's numbers against another's.
Solubility & Reconstitution
| Specification | Value |
|---|---|
| Solubility | Soluble in water and in DMSO; approximately 2 mg/mL in DMSO as reported for the iodide salt |
| Recommended Diluent | Water or DMSO, depending on the research protocol; bacteriostatic water is supplied complimentary with every order |
| Solution Handling | Prepare fresh, keep cold, and avoid repeated freeze-thaw cycles |
Unlike the lipid-conjugated peptides in this catalogue, 5-Amino-1MQ should give a clear solution. Persistent cloudiness is worth investigating rather than expecting. Our vials hold 3 ml, which caps how much diluent can be added — the reconstitution calculator works this out for any target concentration.
Storage & Stability
| Specification | Value |
|---|---|
| Storage — Sealed Vial | Freeze at ≤ −20 °C, sealed, away from light and moisture |
| Shelf Life — Sealed | Approximately 24 months under recommended storage conditions |
| Storage — After Reconstitution | Refrigerate at 2–8 °C |
| In-Use Period | 28–30 days after reconstitution |
| Conditions to Avoid | Heat, direct light, moisture, and repeated freeze-thaw cycles |
Costa Rica's humidity makes storage a live concern rather than a formality. Let a frozen vial reach room temperature fully before breaking the seal, or condensation forms inside it. There is more in storing peptides in tropical climates.
Quality Assurance & Documentation
| Specification | Value |
|---|---|
| Analytical Method | Reverse-phase high-performance liquid chromatography (HPLC) |
| Batch Testing | Independent third-party analysis for identity, purity, and contaminants |
| Certificate of Analysis | Issued per batch — searchable in the COA database |
| Batch / Lot Number | Printed on the vial label and shown on the accompanying Certificate of Analysis |
Note that the purity specification for this compound is ≥98%, not the ≥99% that applies to most peptides in the catalogue. That matches the grade at which the iodide salt is supplied by reference chemical suppliers.
Intended Use & Regulatory Status
| Specification | Value |
|---|---|
| Intended Use | Research Use Only (RUO) — laboratory, analytical, and scientific applications |
| Uses Advised Against | Not for human or veterinary use. Not a drug, food, cosmetic, dietary supplement, or household product. Not for diagnostic or therapeutic use. |
| Evidence Base | Preclinical — cell culture and rodent models, with no controlled human trials of this compound |
| Regulatory Status | Not approved or licensed by the U.S. FDA, the EMA, or Costa Rica's Ministerio de Salud for the prevention, diagnosis, treatment, or cure of any disease |
| Distribution | Supplied within Costa Rica |
Vial Sizes & PDF Downloads
Both sizes are the same material. Each PDF is a print-ready version of this sheet for the specific vial, suitable for filing with research records or attaching to a purchase order.
| Vial Size | Product Code | Product Page | Specification PDF |
|---|---|---|---|
| 5 mg | PCR-A1MQ-5 | 5-Amino-1MQ 5mg | Download PDF |
| 50 mg | PCR-A1MQ-50 | 5-Amino-1MQ 50mg | Download PDF |
Current pricing and stock are on the 5-Amino-1MQ product page, and there is background on the mechanism in the complete guide. Related compounds sit under peptides for weight loss.
Common Questions
Is 5-Amino-1MQ a peptide?
No. It is a small molecule — a single quinolinium ring system with a molecular weight under 300. Peptides are chains of amino acids and are typically ten to a hundred times heavier. It also works differently, inhibiting an enzyme rather than activating a receptor.
Which molecular weight should I use, 159.21 or 286.11?
Use 286.11, the iodide salt, for anything gravimetric — that is what is physically in the vial. The 159.21 figure is the cation alone, which is useful for expressing active species but will under-deliver by roughly 44% if you weigh against it.
Why is the purity specification 98% rather than 99%?
≥98% by HPLC is the grade at which the iodide salt is supplied by reference chemical suppliers, and it is the standard every batch here must meet. Most peptides in the catalogue carry a ≥99% specification; the difference reflects the compound class, not a lower standard of testing.
What colour should the powder be?
Reference suppliers describe the iodide salt as faint red to dark brown. Check the appearance recorded on your lot's Certificate of Analysis rather than relying on colour alone as an identity check.
Does it need bacteriostatic water like the peptides?
It dissolves in water or DMSO depending on your protocol. Bacteriostatic water is included with every order and works for aqueous preparations; DMSO is the usual choice for cell-culture stock solutions.
Is there human clinical data on 5-Amino-1MQ?
No. The published work is in cell culture and rodent models. No controlled human trials of this compound have been reported, which is why it is supplied strictly for laboratory research.
Is this a Certificate of Analysis?
No. This sheet states the specification every batch must meet. The Certificate of Analysis reports what one specific lot actually measured, with a lot number and test date. If you need to document the exact material you received, you need the COA.
Is 5-Amino-1MQ legal in Costa Rica?
It is supplied within Costa Rica for laboratory and research use only, and holds no marketing authorisation from Costa Rica's Ministerio de Salud. We do not ship internationally.
Questions about 5-Amino-1MQ specifications?
If you need a batch certificate, documentation in a specific format for an institutional purchase, or clarification on anything in this sheet, get in touch. We answer every message personally.
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Important disclaimer: The information on this page is general educational and technical content only. It is not medical advice, a prescription, or a personalized recommendation. This specification sheet describes the product as supplied and does not constitute a Certificate of Analysis or a Safety Data Sheet. 5-Amino-1MQ is not approved or licensed by the U.S. FDA, the EMA, or Costa Rica's Ministerio de Salud for any use. The published evidence base for this compound is preclinical: findings come from cell culture and rodent models, no controlled human trials have been reported, and its safety profile in people is not established. Always consult a qualified healthcare professional before beginning any research protocol. Products sold by Peptides Costa Rica are intended for laboratory and research purposes only.
