Semax

Semax is priced at ₡40,903 per 10mg vial at Peptides Costa Rica, in USD. With a 15% bulk discount on orders of five or more vials, the per-vial cost drops to ₡35,190 — a saving of ₡31,050 on a five-vial order (₡207,000 down to ₡175,950). Pairing a single Semax vial with BAC Water, Adamax, or another nootropic in one order crosses the ₡92,000 free-shipping threshold.

Yes. Order five or more Semax 10mg vials in a single order and receive an automatic 15% discount. Five vials normally cost ₡207,000 and drop to ₡175,950 — no tiered minimums, no fine print, applied automatically at checkout.

Adamax is structurally derived from Semax — both contain the ACTH(4-7) fragment associated with cognitive and neuroprotective effects. Semax is the original peptide with a longer track record in research literature, including decades of clinical use in Russia for stroke recovery and ADHD. Adamax is generally regarded as a modified, longer-acting variant designed for improved stability and blood-brain barrier crossing. Researchers often choose Semax when they want the more thoroughly documented compound; Adamax when they want extended action. Both are available at Peptides Costa Rica — Semax 10mg at ₡41,400 and Adamax 5mg at ₡75,900.

Semax is studied for cognitive performance — memory, attention, learning, and focus enhancement through BDNF upregulation; neuroprotection — protecting neurons from oxidative damage, hypoxic stress, and ischemic injury (its primary clinical application in Russia, where it has been approved for ischemic stroke treatment); ADHD and attention disorder research, with documented Russian clinical research in pediatric ADHD applications; stress adaptation and resilience to mental fatigue through its ACTH(4-7)-derived adaptogenic effects; and depression and mood research as a secondary application area examining its modulation of monoaminergic signaling.

Semax is a heptapeptide consisting of the ACTH(4-7) fragment (Met-Glu-His-Phe) with an attached Pro-Gly-Pro tail that significantly extends its biological half-life. Its primary mechanism involves upregulation of brain-derived neurotrophic factor (BDNF) — a protein essential for neuron growth and synaptic plasticity. Beyond BDNF, Semax modulates dopaminergic and noradrenergic signaling pathways associated with attention and cognitive arousal, influences expression of neuroprotective genes including those for antioxidant enzymes, and provides direct neuroprotective effects in ischemic and oxidative stress models — without the hormonal effects of the full ACTH peptide.

Semax was developed in the 1980s at the Institute of Molecular Genetics in Moscow and has one of the longest clinical research histories of any peptide in this catalog. It has been approved in Russia for ischemic stroke treatment for several decades and has been studied in formal Russian clinical research for ADHD in pediatric populations, post-stroke rehabilitation, and cognitive enhancement applications. While it remains primarily a research compound outside of Russia, its extensive documented use makes it one of the more thoroughly characterized nootropic peptides available.

Unreconstituted Semax vials should be stored refrigerated at 2–8°C in lyophilized (powder) form, protected from light and moisture. Freezing is suitable for long-term storage. Once reconstituted with bacteriostatic water, keep the solution refrigerated and use within the timeframe outlined in your research protocol. Semax has been studied with both subcutaneous and intranasal administration routes in research literature — handling and reconstitution should align with the protocol's chosen route.

Orders inside Costa Rica are typically delivered within 2–4 business days. You'll receive tracking once shipped — no customs delays or import fees since everything is fulfilled domestically.