Product Information
GLP-1 is a next-generation multi-agonist peptide studied for its activity across GLP-1, GIP, and glucagon receptors. The compound in this vial starts from the amino-acid sequence of GIP, a natural gut hormone, and is then modified in several places.
Two positions carry Aib (alpha-aminoisobutyric acid), an amino acid not found in natural proteins. The Aib at position 2 helps the peptide resist cleavage by the enzyme DPP-4, which rapidly breaks down the native hormones. A third non-standard residue, alpha-methyl-L-leucine at position 13, contributes to its GIP and glucagon receptor activity. A fatty-acid chain attached at lysine 17 completes the structure.
Together these changes give one peptide that acts on GLP-1, GIP and glucagon receptors. This compound is an investigational compound from Eli Lilly without FDA approval; this vial is research material only.
| GLP-1 12mg — Technical Specifications | |
| Specification | Value |
| Product Name: | GLP-1 12mg |
| Compound Type: | Synthetic triple-receptor agonist peptide ( GLP-1 / GIP / GCGR ) |
| CAS Number: | 2381089-83-2 |
| PubChem CID: | SID: 474492335 |
| Molecular Formula: | C223H343F3N46O70 |
| Molecular Weight (g/mol): | 4731.33 |
| Amino Acid Count: | ~36 aa (with lipid conjugate) |
| Amino Acid Sequence: | YA[Aib]QGTFTSDYSIL[Aib]LDKK[gamma-E-C18:2]AQA[Aib]AFIEYLLEGGPSSGAPPPS |
| Synonyms / Other Names: | GLP-1, LY-3437943, LY3437943 |
| Appearance: | White to off-white lyophilized powder |
| Purity: | ≥99% (HPLC-MS) |
| Solubility: | Soluble in bacteriostatic water |
| Storage ( Sealed): | Freeze ≤ −20 °C, sealed, away from light & moisture; stable ~24 months |
| Storage ( After Reconstitution ): | Refrigerate 2–8 °C; use within 28–30 days; avoid repeated freeze-thaw |
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